800A/805A: 体外肌肉测量装置
800A(小鼠)和805A(大鼠)体外肌肉仪器分别是为配合我们的300C和305C双模式肌肉杠杆使用而设计的。这些测试系统设计灵活，可以在组织浴中对完整的肌肉进行垂直、体外测量。
浴槽被安装在一个垂直的DeepL，允许研究人员提高和降低浴槽，以便在安装、移除和测量时容易接触到组织。浴槽是受温度控制的，并伴有一个充氧的气泡系统。双重细/粗控制允许组织的准确定位和调整静止张力或肌肉长度。
为了方便研究人员，安装面板上的T型槽允许所有的夹子根据需要重新排列。同样，额外的仪器设备也可以很容易地添加到安装面板上。该仪器设计用于长寿命，由抗腐蚀材料制成，并注意到一些细节，如罐装电极以防止腐蚀。
● 为小鼠和大鼠定制
● 垂直滑板，在安装和测量时容易接触到组织
● 双重粗/细DeepL，精确控制下层组织钳。
● 充氧和温控浴
● 内置铂金电极的电极架
● T型槽设计，可灵活地重新配置，材料耐腐蚀
-
Anderson, Christopher V. et al. “Thermal effects on the performance, motor control and muscle dynamics of ballistic feeding in the salamander Eurycea guttolineata.” Journal of Experimental Biology (2014) DOI: 10.1242/jeb.105437
-
Reimche et al “The road not taken: Evolution of tetrodotoxin resistance in the Sierra garter snake (Thamnophis couchii) by a path less traveled” Molecular Ecology (2022) DOI: 10.1111/mec.16538
-
Dyle, Michael C. et al. “Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy.” The Journal of Biological Chemistry (2014) DOI: 10.1074/jbc.M114.556241
-
Jo-Avila, Miguel et al. “Relaxant effect of superimposed length oscillation on sensitized airway smooth muscle.” American Journal of Physiology: Lung Cellular and Molecular Physiology (2015) DOI: 10.1152/ajplung.00218.2014
-
Smith et al. “Novel γ-sarcoglycan interactors in murine muscle membranes” Skeletal Muscle (2022) DOI: 10.1186/s13395-021-00285-2
-
Sreetama et al. “Membrane Stabilization by Modified Steroid Offers a Potential Therapy for Muscular Dystrophy Due to Dysferlin Deficit” Molecular Therapy (2018) DOI: 10.1016/j.ymthe.2018.07.021
-
Hakim, Chady H., Nalinda B. Wasala and Dongsheng Duan. “Evaluation of muscle function of the extensor digitorum longus muscle ex vivo and tibialis anterior muscle in situ in mice.” Journal of Visualized Experiments (2013) DOI: 10.3791/50183
-
Olberding & Deban “Effects of temperature and force requirements on muscle work and power output” The Journal of Experimental Biology (2017) DOI: 10.1242/jeb.153114
-
Vassilajos et al. “Deletion of muscle IGF-I transiently impairs growth and progressively disrupts glucose homeostasis in male mice” The FASEB Journal (2019) DOI: 10.1096/fj.201800459R
